EDWARDS SYNDROME
T
RISOMY 18

Definition: Chromosomal defect when there is a third chromosome on the 18th pair.

Characteristics
-causes major physical abnormalities and severe mental retardation, and very few children afflicted with this disease survive beyond a year.
-small head and jaw
-low set ears
-kidney problems
-delayed growth
-pocket of fluid on the brain
-strawberry shaped head







trisomy_baby.jpg
baby affected with Edwards Syndrome

Why it occurs...
-3 chromosomes are found on the 18th pair, instead of only 2
-Parents don't cause the disease.
-nondisjunction

external image Trisomy18.gif
(karyotype chart of someone who has Trisomy 18)

Different Variations of Trisomy 18
Types of Edwards Syndrome: Full, partial, mosaic
-Partial and mosiac are rare.
-Full is the most common, it occurs in 95% of all cases
.

Random Facts
-1 in 3,000 babies are born with Edwards syndrome.
-Losses of babies with Trisomy 18 are more likely to occur in the 2nd and 3rd trimesters of pregnancy
-Edwards Syndrome is more common is females, than males.
-Women over the age of 30 have a greater risk of having a baby with edwards disease than a women under 30 years old.
-The higher the birth weight the better the chance the baby will live.
-2nd most common trisomy disease next to Down Syndrome (Trisomy 21)

(Video clip explaining trisomy 18)

Cures

There is no cure to Edwards syndrome.
-there is no scientific method to prevent chromosomal disorders
-parents cannot do anything to prevent Edwards Syndrome

How its diagnosed
Screening and diagnostic.

Screening tests indicate a risk or liklihood that Edwards syndrome is present.-based on probability
-using Ultrasound or AFP

Diagnostic tests check actual cells and can determine if trisomy 18 is present.
-using CVS or Amnio

Concerning the Child
-diagnosed prior to birth: parents should schedule an appt. with a genetic counsler
-diagnosed after birth: specialized care will be required by your doctor and hospital

Babies born with Edwards disease are put in supportive care with the hope that they will comfortable rather than in pain for their short lives.

trisomy_18_ribbon.jpg
Recommendations for those with a child who has been diagnosed
-take time in making critical decisions
-ask questions and find answers
-know that every pregnancy and child is different
-find medical professionals that are on your side
-read other parent's stories

To read stories follow this link >> **http://www.trisomy18.org/site/TR**

(Real life story of a family experiencing Edwards Syndrome)



Bibliography:
http://www.youtube.com/watch?v=8lC4p52bgyE

http://www.youtube.com/watch?v=cteTcuI-xYI
http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/genetics/trisomy.html
http://www.biology.iupui.edu/biocourses/N100/images/Trisomy18.gif
http://www.trisomy18.org/site/PageServer?pagename=homepage
http://www.stickershoppe.com/mm5/graphics/00000001/MLRTRIS.jpg

cv-8f-lar: I loved the blue and green theme of your font! The bullets made everything simple to understand and the pictures were a huge help! Nice going!! :)
cv-8f-krb: A very well thought out page with a lot of info. and good pic.
cv-8f-klba: This is a very nice page with the color layout. It would be even better if you added more pictures or examples. You did a nice job!
cv-8f-jtb: This is a very gratifying page!!! You kept it simple and to the point, which made it easy for me :)

cv-8f-kpi I hadn't known what Edwards syndrom was, but this page made me well-known to the disease. The layout was really good, and the pictures and video really taught through a visual perspective.
cv-8f-bop: I could understand well about this disease~! i like this page! good job~
cv-8f-ctk: Awesome page! it is very helpful on learning what Edward's Syndrom is all about. it is simple, yet amazingly brilliant! :)
cv-8f-ecb: I love this page:) the colors are great and everything was easy to understand. the video's were very helpful too!